Sunday, December 2, 2018

The Not-So-Phantom Menace of Antimicrobial Resistance (AMR)


                Antimicrobial resistance (AMR), also known as antibiotic resistance has been a rampant problem in the 21st century (Davies S.C., Gibbens N., 2013). Due to reckless prescribing of antibiotics in the past for other infections besides bacterial—such as fungal and viral infections—has bred multiple strains of AMR bacteria such as staphylococcus aureus (MRSA or ‘golden staph’) and Neisseria gonorrhoeae (cause of gonorrhea) that are completely resilient to benzyl penicillin, which originally was able to control these infections.
                When antimicrobials are used to fight an infection that will not be damped and killed by the medication, those pathogens remain within the body why the possibility of other helpful microbes, such as the bacteria in your intestines that aid in digestion, increases. As the symbiotic bacteria die off, there is less competition for the “bad bacteria” which will lead to proliferation and worsening symptoms.
                These resistant strains pose a huge economic and health consequence around the world, becoming a top issue of multiple countries.  With AMR multiple lives are put at risk of injury, loss and death. There have been predictions of a needed shift and redistribution of resources, balancing of benefits and burdens, as well as changing the structure of institutes as well as the behaviors of governments, corporations, scientists as well as clinicians and patients (Littmann, J., 2015). The promotion of good hygiene practices and over-prescribing antibiotics can only do so much. A report states from an interview with Michele Cecchini of the Organization for Economic Cooperation and Development’s (OECD) health division states that “$2 per person per year could pay for itself within just one year and end up saving $4.8 billions of dollars per year in OECD countries (Koukakis, N., 2018).” In the name of ethics, and the fate of future generations to come, there needs to be something done to prevent more bacteria to become antibiotic resistant, and to work on ways to counteract the strains that are already AMR.


Davies S. C., Gibbens N. (2013). UK Five Year Antimicrobial Resistance Strategy 2013–2018. London: Department of Health.
Littmann, J. (2015, September 30). The Ethical Significance of Antimicrobial Resistance. Public Health Ethics. 2015 Nov, 8(3): 209-224.
Koukakis, N. (2018, November 08). Superbugs pose a dangerous, $65 billion threat to the US health-care system. Retrieved from https://www.cnbc.com/2018/11/07/superbugs-dangerous-65-billion-threat-to-the-us-health-care-system.html
OECD (2018), Stemming the Superbug Tide: Just A Few Dollars More, OECD Health Policy Studies, OECD Publishing, Paris, https://doi.org/10.1787/9789264307599-en.

2 comments:

  1. Purple,

    I couldn't agree more with you. It is definitely a huge problem that we are facing with antibiotic resistance bacteria and it is sad to see that we are spending so much money on trying to fight these "super bugs". I also found a article that they are trying different antibiotic combination to fight off infection now. They found that four or five type of antibiotics working together are proven to be effective in fighting infection. But, honestly, I do not think that it would help in the long-term. Eventually, these microbes will adapt and counter the use of these antibiotics which would result in us spending more money on treatment. It is like we are repeating the same mistake over again. We need to find a better alternative to treating infection or avoiding it.

    https://www.medicalnewstoday.com/articles/322974.php

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  2. Great topic! Antibiotics are a cornerstone in modern medicine, yet the over prescription of antibiotics has led to antibiotic-resistant infections, killing 23,000 people per year. Data from the CDC revealed that 1 in 3 antibiotic prescriptions are unnecessary. Continued over prescription rates such as this could potentially lead to superbug outbreaks that could render antibiotics ineffective. I recently came across an interesting article that warned that antibiotics pumped into agriculture and farms animals are also a huge contributing factor, something I never even thought of! The agriculture department actually confirmed that almost 80 percent of all antibiotics sold in the United States are used in animal agriculture!! This is crazy! So maybe efforts to combat antibiotic resistance should be aimed at not only reducing the amount of antibiotics prescribed in hospitals but also those used in agriculture.

    CDC Press Releases. (2016, January 1). Retrieved December 5, 2018, from https://www.cdc.gov/media/releases/2016/p0503-unnecessary-prescriptions.html
    Fleming-Dutra, K. E., Hersh, A. L., Shapiro, D. J., Bartoces, M., Enns, E. A., File, T. M., … Hicks, L. A. (2016). Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011. JAMA, 315(17), 1864–1873. https://doi.org/10.1001/jama.2016.4151
    Strom, S. (2018, October 19). Report on U.S. Meat Sounds Alarm on Resistant Bacteria. The New York Times. Retrieved from https://www.nytimes.com/2013/04/17/business/report-on-us-meat-sounds-alarm-on-superbugs.html

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